Lomachenko (17-3, 11 KOs), a three-weight world champion and former unified lightweight king, returns following his close call against then-undisputed lightweight champion Devin Haney last May. Kambosos (21-2, 10 KOs), who lost a pair of undisputed bids to Haney on Australian soil in 2022, defeated Maxi Hughes last July in Shawnee, Oklahoma.
In a world championship special attraction, just before the main event, Great Britain’s WBA bantamweight world champion Nina Hughes (6-0, 2 KOs) makes her second world title defense against Australian former world champion Cherneka Johnson (15-2, 6 KOs).
The ESPN-televised broadcast kicks off with the return of Andrew Moloney (26-3, 16 KOs), who takes on Mexican former world champion Pedro Guevara (41-4-1, 22 KOs) for the vacant WBC Interim junior bantamweight championship.
Lomachenko-Kambosos, Hughes-Johnson and Moloney-Guevara will be broadcast on ESPN, ESPN Deportes & ESPN+ at 10 p.m. ET/7 p.m. PT.